Abstract:Gastric variceal bleeding is one of the leading causes of death in cirrhotic patients with portal hypertension. Endoscopic cyanoacrylate injection serves as the primary treatment for gastric varices, but faces clinical challenges such as technical difficulty, suboptimal efficacy, and relatively high risks. Endoscopic ultrasound (EUS)-guided coil embolization is increasingly used in clinical practice due to unique advantages in precision, however, no specific guidelines or consensus statements are available to standardize its clinical application. In 2025, EUS Study Group and Liver Disease Collaboration Group of Digestive Endoscopy Branch of Chinese Medical Association organized extensive discussions among national authoritative experts and jointly developed this consensus. It addresses 10 core clinical issues with 26 statement recommendations, aiming to standardize the clinical practice of EUS-guided coil embolization for gastric varices and to guide physicians in performing this novel technique safely, smoothly, and effectively.