胃肠间质瘤内镜治疗的现况

A Review of the Current Status of Endoscopic Treatment for Gastrointestinal Stromal Tumors

摘要:

胃肠间质瘤（GIST）是一类具有恶性潜能的上皮下病变，在消化内镜检查中常以黏膜下肿瘤的形式被发现，对于可切除的胃肠间质瘤常选用外科手术切除。而随着内镜技术的发展，消化内镜除了在诊断中发挥重要作用外，在胃肠间质瘤治疗方面的潜力与价值也逐渐显现，以内镜黏膜下剥离术及其衍生技术为主的内镜治疗方法的逐步发展使得GIST切除更为简捷及微创，术式的创新让内镜能应用于各种类型的肿瘤切除。研究GIST内镜治疗发展过程中面临的瓶颈和相应的突破将有利于了解不同切除方式的适用范围并明确未来的研究方向。

Abstract:

Gastrointestinal stromal tumors (GIST) are a group of subepithelial lesions with malignant potential that are frequently detected as submucosal tumors during gastrointestinal endoscopy. Surgery is often considered for resectable GIST. With the development of endoscopic techniques, the gastrointestinal endoscopy’s potential and value in treating GIST have gradually come into focus, in addition to its important role in diagnosis. Endoscopic submucosal dissection and its derivative techniques have simplified GIST resection and minimized invasiveness. Furthermore, the innovation of the procedures allowed endoscopy to be applied to the resection of various types of tumors. Reviewing the current status of the endoscopic treatment of GIST will help to understand the application of different resection techniques and clarify the areas for further investigation.