探头式共聚焦激光显微内镜在小肠疾病中的特征

摘要:

目的：探讨探头式pCLE在小肠疾病，尤其是小肠肿瘤中的图像特征表现。 方法：回顾性纳入2023年12月～2024年8月在我院接受小肠镜和pCLE检查的小肠患者，使用器械为富士公司EN-580T双气囊小肠镜，采用精微视达的倍晰?共聚焦显微内窥镜进行图片的提取，最终依据病理诊断作为诊断金标准进行分析诊断。 结果：我们收集20例小肠疾病患者的资料，女性15例，男性5例，行经口小肠镜检查患者15例，行经肛小肠镜检查患者5例，收集病例中包括小肠淋巴瘤（6例，30%），空肠腺癌（4例，20%），脂肪瘤（2例，10%），P-J综合征（5例，25%），多发炎性纤维性息肉（1例，5%），蓝色橡皮泡痣综合征（1例，5%）,炎症性肠病（1例，5%），pCLE对隐窝，上皮，腺体，血管的纹理、形态、排列等具有显著优势，可很好的区别上述疾病。 结论：本文首次提供了pCLE在小肠肿瘤中的特征，可为小肠肿瘤疾病的早期诊断提供帮助。

Abstract:

Objective: To explore the imaging features of probe based pCLE in small intestinal diseases, especially small intestinal tumors. Method: A retrospective study was conducted on small intestine patients who underwent colonoscopy and pCLE examination at our hospital from December 2023 to August 2024. The instrument used was the Fuji EN-580T double balloon small intestine endoscope, which was performed using a high-definition microscope ? The confocal microscope is used to extract images, and the final analysis and diagnosis are based on pathological diagnosis as the gold standard for diagnosis. Result: We collected data from 20 patients with small intestinal diseases, including 15 females and 5 males. Among them, 15 patients underwent oral small intestinal endoscopy and 5 patients underwent anal small intestinal endoscopy. The collected cases included small intestinal lymphoma (6 cases, 30%), jejunal adenocarcinoma (4 cases, 20%), lipoma (2 cases, 10%), P-J syndrome (5 cases, 25%), multiple inflammatory fibrous polyps (1 case, 5%), blue rubber bubble nevus syndrome (1 case, 5%), and inflammatory bowel disease (1 case, 5%). pCLE has significant advantages in the texture, morphology, and arrangement of crypts, epithelium, glands, and blood vessels, and can effectively distinguish the above diseases. Conclusion: This article provides for the first time the characteristics of pCLE in small intestinal tumors, which can assist in the early diagnosis of small intestinal tumor diseases.