Abstract:Objective: To investigate whether video-based guidance for colon preparation in Tibetan populations can improve the quality of bowel preparation and increase the Polyp Detection Rate (PDR) during colonoscopy. Methods: A prospective, endoscopist-blind, randomized controlled trial was conducted. Patients who underwent colonoscopy at the Yushu Tibetan Autonomous Prefecture People’s Hospital from March 1, 2024 to July 31, 2024, were enrolled. Patients were randomly divided into two groups: the video-based education group and the text-based education group. The Ottawa Bowel Preparation Score was used to evaluate the quality of colon preparation, and PDR was compared between the two groups. Logistic univariate, multivariate, and subgroup analyses were conducted to examine the relationship between the method of education and PDR. Results: A total of 149 patients were included, with 79 in the text-based education group and 70 in the video-based education group. There was no significant difference in Ottawa scores between the two groups, but the PDR was 1.3% in the text-based group and 14.3% in the video-based group, showing a statistically significant difference. Logistic univariate analysis indicated that video-based education and the Ottawa score for the transverse colon were risk factors for PDR. Logistic multivariate analysis confirmed that video-based education was a risk factor for PDR, with stable results across multiple models. Conclusion: Video-based education can improve PDR in the Tibetan population.