内镜黏膜下剥离术在原发性胃肠道淋巴瘤诊断中的价值

Diagnostic value of endoscopic submucosal dissection for primary gastrointestinal lymphoma

摘要:

目的 探讨内镜黏膜下剥离术（endoscopic submucosal dissection，ESD）对原发性胃肠道淋巴瘤（primary gastrointestinal lymphoma，PGIL）的诊断价值。方法 回顾分析2021年1月至2023年12月就诊于复旦大学附属中山医院及复旦大学附属中山医院厦门医院诊断为疑似PGIL的37例患者的临床及病理资料，对比首次内镜下常规活检与ESD活检对诊断PGIL准确率的差异性。结果 首次内镜下常规活检明确诊断为PGIL 6例，确诊率16.22%（6/37）；共22例患者行ESD活检，其中确诊为PGIL者20例，确诊率90.91%（20/22），明显高于首次内镜下常规活检的确诊率，差异有统计学意义（χ²=31.228，P<0.05）。结论 ESD对PGIL的诊断具有较好的临床应用价值。

Abstract:

Objective To analyze and explore the diagnostic value of endoscopic submucosal dissection (ESD) for primary gastrointestinal lymphoma (PGIL). Methods A retrospective analysis was conducted on the clinical and pathological data from 37 patients with suspected PGIL and admitted to Zhongshan Hospital, Fudan University and Xiamen Hospital, Zhongshan Hospital, Fudan University between January 2021 and December 2023. The diagnostic accuracy for PGIL of initial endoscopic conventional biopsies was compared with that of ESD biopsies. Results Among these patients, 6 were diagnosed as having primary gastrointestinal lymphoma by routine endoscopic biopsy, with a diagnostic rate of 16.22% (6/37). Of the 22 patients who underwent ESD, 20 were diagnosed as having primary gastrointestinal lymphoma, achieving a diagnostic rate of 90.91% (20/22), which was significantly higher than that of initial endoscopic routine biopsies (χ²=31.228, P<0.05). Conclusion ESD demonstrates significant diagnostic value for PGIL.