Abstract:Colorectal cancer is one of the common malignant tumors with a rising incidence in China. Screening colorectal adenomas or early colorectal cancer is the prerequisite and key to reduce the incidence and mortality of colorectal cancer. In recent years, with the increasing application of noninvasive diagnostic biomarkers for colorectal neoplasms and accumulating evidence of relevant research, led by National Clinical Research Center for Digestive Diseases, supported by National Key Laboratory of Digestive Health, in conjunction with Gastroenterologist and Hepatologist Branch of Chinese Medical Doctor Association, multidisciplinary experts including gastroenterology, general surgery, digestive endoscopy and oncology jointly developed this consensus to provide guidance for the clinical application of noninvasive diagnostic biomarkers for colorectal neoplasms in China.