Abstract:Esophageal and gastric cancers are two of the common malignant tumors in Midwest China, posing a serious threat to public health. In recent years, magnifying endoscopy has been widely used in the screening and diagnosis of early esophageal cancer and gastric cancer. Through conducting multiple discussions with numerous experts, and combining the latest research progress in the diagnosis and treatment of early upper gastrointestinal cancer by magnifying endoscopy, the consensus of magnifying endoscopy for upper gastrointestinal tumors in high-risk populations in Midwest China was developed. The expert opinion aims to further increase the detection rate of early upper gastrointestinal cancer and promote the standardized application of magnifying endoscopy.