磁控胶嚢胃镜与传统胃镜对儿童胃及十二指肠检查的对比分析

Comparison of magnetically controlled capsule gastroscopy and conventional gastroscopy for gastric and duodenal examination of children

摘要:

目的 探讨磁控胶嚢胃镜（magnetically controlled capsule gastroscopy，MCCG）在儿童胃、十二指肠检查中的临床应用价值、安全性及与传统胃镜间的差异。方法 回顾性分析2020年3月—2022年3月期间在上海市儿童医院门诊或住院的腹痛伴幽门螺杆菌感染的160例8~16岁患儿临床资料。患儿根据胃镜检查方法不同分为MCCG检查组及传统胃镜检查组各80例。观察分析两组患儿上消化道病变的检出情况、检查时间、耐受度及安全性。结果 两组患儿分别顺利完成MCCG检查79例及传统胃镜检查78例，病变检出率两组比较，食管［1.3%（1/79）比1.3%（1/78），χ2=0.000，P>0.999］、胃［87.3%（69/79）比91.0%（71/78），χ2=0.552，P=0.327］、十二指肠［15.2%（12/79）比19.2%（15/78），χ2=0.450，P=0.533］，组间差异无统计学意义。MCCG组与传统胃镜组检查时间比较差异有统计学意义［72.0（41.0，109.5）min比6.0（4.3，7.0）min，U=24，P<0.001］。两组患儿均无不良事件发生。结论 MCCG对于胃部及十二指肠疾病的检出率与传统胃镜无明显差异，且安全、稳定，可作为诊断儿童胃及十二指肠疾病的检查工具。

Abstract:

Objective To investigate the clinical application value and safety of magnetically controlled capsule gastroscopy (MCCG) in gastric and duodenal examination of children in comparison with conventional gastroscopy. Methods Data of 160 outpatients or inpatients with abdominal pain accompanied by Helicobacter pylori infection aged 8-16 who underwent either MCCG or conventional gastroscopy in Shanghai Children''s Hospital from March 2020 to March 2022 were retrospectively analyzed. Children were divided into the MCCG group (n=80) and the conventional gastroscopy group (n=80) according to different examination methods. The detection and examination time of lesions in upper gastrointestinal tract, tolerance and safety between the two groups were analyzed. Results MCCG was successfully performed in 79 children and conventional gastroscopy was successfully performed in 78 children, respectively. The positive detection rates were 1.3% (1/79) and 1.3% (1/78) in the esophagus (χ2=0.000, P>0.999), 87.3% (69/79) and 91.0% (71/78) in the stomach (χ2=0.552, P=0.327) , 15.2% (12/79) and 19.2% (15/78) in duodenum (χ2=0.450, P=0.533) with no significant difference between the two groups. There was no significant difference in the examination time [72.0 (41.0, 109.5) min VS 6.0 (4.3, 7.0) min,U=24,P<0.001] in the MCCG group and the conventional gastroscopy group. No adverse event occurred in either group. Conclusion There is no significant difference in the detection rate of gastric and duodenal lesions between the MCCG group and the conventional gastroscopy group. MCCG is safe and stable, and can be used as an diagnostic tool for gastric and duodenal diseases in children.