Abstract:Abstract: Objective: To formulate a strategy for the prevention and control of COVID-19 pneumonia in endoscopic centers of large general hospitals. Methods: Establish a special prevention and control team; full staff training; quickly start the emergency mechanism; adjust the workload and model, establish a three-level screening mechanism for patients; strengthen occupational protection; improve protection technology. Results: Our center did not stop receiving patients, and a total of 2009 cases were screened. Screening for 2 patients with fever; one patient with asymptomatic COVID-19 pneumonia was detected by CT scan; no COVID-19 pneumonia infection occurred in hospital. Conclusion: Comprehensive detection and protection of doctors, nurses and patients. Provide a safe medical treatment environment for COVID-19 pneumonia patients by “early detection, early diagnosis, and early isolation”. We achieved COVID-19 pneumonia zero infection in the hospital.