Abstract:Gastrointestinal schistosomiasis is an acute or chronic inflammatory disease caused by schistosome eggs invading the digestive tract mucosa and depositing in the stomach wall. Gastrointestinal schistosomiasis is rare and lacks of specific clinical and endoscopic performances, which leads to difficulties of clinical diagnosis. Clinicians have insufficient understanding of their clinical and endoscopic findings, so lesions are often misdiagnosed. With the popularity of gastroendoscopy and the development of diagnostic techniques, there has been an increase in the number of reported cases of this kind of disease. There have been different opinions on whether gastric schistosomiasis is a precancerous lesion, the relationship between gastric schistosomiasis and gastric cancer is still not clear. A case of gastric schistosomiasis misdiagnosed as early gastric cancer(EGC) under electron-staining magnifying endoscopy (blue laser imaging) in my hospital is reported below to improve clinicians understanding of the disease.