人工智能电子染色技术在声带白斑及食管病变诊断中的临床应用

Diagnostic value of Fuji intelligent color enhancement on vocal leukoplakia and esophageal diseases

摘要:

目的 探讨人工智能电子染色技术(FICE)在声带白斑及食管病变诊断中的临床应用。方法 2014年1月至2016年1月行常规电子喉镜检查疑诊声带白斑的50例患者，利用FICE行声带与食管的精细检查，评估FICE对声带白斑的诊断价值。结果 50例患者常规喉镜检查发现病变50处，FICE发现病变52处。FICE模式与白光模式对声带病变表面毛细血管形态评分和病变边界清晰度评分比较，差异均有统计学意义（P值均〈0.05）。对声带病变性质的诊断，FICE放大内镜模式与病理诊断的符合率高于白光模式[89.4%（42/47）比68.1%（32/47），P=0.01]。50例可疑声带白斑患者中，合并胃食管反流病者31例，给予质子泵抑制剂治疗3个月后复查，声带白斑减轻16例，消失13例，无明显变化者2例。结论 FICE在声带白斑病变的诊断方面，较常规电子喉镜及普通白光胃镜具有更高的临床应用价值。

Abstract:

Objective To study the clinical application of Fuji intelligent color enhancement (FICE) on the diagnosis of vocal leukoplakia and esophageal diseases. Methods A total of 50 patients suspected with vocal leukoplakia by electronic laryngoscopy were enrolled for undergoing meticulous examination of vocal cords and esophagus using FICE from January 2014 to January 2016. The diagnostic value of FICE for vocal leukoplakia were analyzed. Results Among the 50 patients, 50 lesions were found using laryngoscopy and 52 lesions were found using FICE. There were significant differences between FICE mode and white light mode on capillary pattern score and lesion boundary resolution score (all P<0.05). The diagnostic coincidence rate of FICE mode with pathology was higher than that of white light mode [89.4% (42/47) VS 68.1% (32/47), P=0.01]. Among the 50 patients suspected with vocal leukoplakia, 31 combined with gastroesophageal reflux disease, and were given proton-pump inhibitor treatment. In the follow-up after three months, lesions of 16 cases alleviated, 13 cases disappeared, and 2 cases had no significant changes. Conclusion FICE has a higher clinical value than conventional laryngoscopy and white light endoscopy on the diagnosis of vocal leukoplakia.